医学院
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| 导师代码： |
21640
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| 导师姓名： |
卢元珺
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| 性 别： |
女 |
| 特 称： |
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| 职 称： |
助理研究员
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| 学 位： |
博士学位
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| 属 性： |
专职 |
| 电子邮件： |
yjlu@uestc.edu.cn
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| 学术经历：
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教育背景
博士，香港大学
硕士，中南大学
本科，中南大学
荣誉与奖项
1. HKU Foundation Award for Outstanding Research Postgraduate Students, 2022/2023
2. YS and Christabel Lung Postgraduate Scholarship, 2022/2023
3. YS and Christabel Lung Postgraduate Scholarship, 2021/2022
4. Tianjiang Cup Li Shizhen Youth Outstanding Thesis Award, 2022
学术会议
1. Invited Poster Presenter, The 13th Pong Ding Yuen International Symposium on Traditional Chinese Medicine, The University of Hong Kong, Hong Kong, March 2026
2. Oral Presenter, The 18th International Postgraduate Symposium on Chinese Medicine, Hong Kong, August 2022
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| 个人简介：
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卢元珺，理学博士，副研究员，硕士生导师，先后于中南大学获得学士与硕士学位，并于香港大学取得博士学位。专注于肿瘤靶向治疗耐药的分子机制和中药抗肿瘤的药理学研究。主持国家自然科学基金青年项目1项，四川省科技厅港澳台科技创新合作项目1项，入选2024年度成都市“蓉漂计划”创新青年人才。近五年在Molecular Cancer, Drug Resistance Updates, Journal of Experimental & Clinical Cancer Research, Journal of Advanced Research 等双一区国际期刊发表论文16篇。参编《基礎與臨床中藥毒理學》和《Macrophage Activation-Biology and Disease》。
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| 科研项目：
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1. 国家自然科学基金——青年科学基金项目（C类）（2026.01—2028.12），30万，主持
2. 四川省科技厅港澳台科技创新合作项目（2024.01-2025.12）, 20万，主持
3. 四川省肿瘤医院优秀青年基金（2024.01-2025.12），10万，主持
3. 四川省肿瘤医院引进人才配套经费，100万，主持
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| 研究成果：
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1.X Xu, C Zhang, Y-T Chan, Yuanjun Lu [4th author], et al.｜Targeting myoferlin by 6-shogaol inhibition regulates hyperglycemia-induced retinal vascular dysfunction｜Phytomedicine｜2026｜2025 JIF: 11.3｜Article 158541;
2. Yuanjun Lu [1st author], Y Wu, X Xu, et al.｜Cancer-associated fibroblasts: central players in cancer hallmarks and therapeutic resistance｜Cell Communication and Signaling｜2025｜2025 JIF: 11.6｜23(1): 534;
3. Yuanjun Lu [1st author], S Ma, Y-T Chan, et al.｜Epigenetic orchestration of cancer-immune dynamics: mechanisms, technologies, and clinical advancements｜Journal of Advanced Research｜2025｜2025 JIF: 17.1;
4. Y-T Chan, J Wu, Yuanjun Lu [3rd author], et al.｜Loss of LncRNA LINC01056 leads to sorafenib resistance in HCC｜Molecular Cancer｜2024｜2025 JIF: 42.2｜23(1): 74;
5. J Wu, H-Y Tan, Y-T Chan, Yuanjun Lu [4th author], et al.｜PARD3 drives tumorigenesis through activating Sonic Hedgehog signalling in tumour-initiating cells in liver cancer｜Journal of Experimental & Clinical Cancer Research｜2024｜2025 JIF: 14.3｜43(1): 42;
6. Yuanjun Lu [1st author], Y-T Chan, J Wu, et al.｜CRISPR/Cas9 screens unravel miR-3689a-3p regulating sorafenib resistance in hepatocellular carcinoma via suppressing CCS/SOD1-dependent mitochondrial oxidative stress｜Drug Resistance Updates｜2023｜2025 JIF: 22.0｜71: 101015;
7. Yuanjun Lu# [co-first author], Y Liu# [co-first author], J Lan, et al.｜Thioredoxin-interacting protein-activated intracellular potassium deprivation mediates the anti-tumour effect of a novel histone acetylation inhibitor HL23, a fangchinoline derivative, in human hepatocellular carcinoma｜Journal of Advanced Research｜2023｜2025 JIF: 17.1｜51: 181–196;
8. Yuanjun Lu [1st author], Y-T Chan, H-Y Tan, et al.｜Epigenetic regulation of ferroptosis via ETS1/miR-23a-3p/ACSL4 axis mediates sorafenib resistance in human hepatocellular carcinoma｜Journal of Experimental & Clinical Cancer Research｜2022｜2025 JIF: 14.3｜41(1): 1–17;
9. Y-T Chan, Yuanjun Lu [2nd author], J Wu, et al.｜CRISPR-Cas9 library screening approach for anti-cancer drug discovery: overview and perspectives｜Theranostics｜2022｜2025 JIF: 14.9｜12(7): 3329;
10. N Wang, H-Y Tan, Yuanjun Lu [3rd author], et al.｜PIWIL1 governs the crosstalk of cancer cell metabolism and immunosuppressive microenvironment in hepatocellular carcinoma｜Signal Transduction and Targeted Therapy｜2021｜2025 JIF: 81.2｜6(1): 86;
11. Yuanjun Lu [1st author], Y-T Chan, H-Y Tan, et al.｜Epigenetic regulation in human cancer: the potential role of epi-drug in cancer therapy｜Molecular Cancer｜2020｜2025 JIF: 42.2｜19: 1–16;
12. Yuanjun Lu [1st author], H-Y Tan, N Wang, et al.｜Polarization of Tumor-Associated Macrophages by Chinese Medicine Intervention: Mechanisms and Applications｜Macrophage Activation—Biology and Disease｜IntechOpen｜2019｜Book chapter; JIF not applicable.
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| 专业研究方向：
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| 专业名称 |
研究领域/方向 |
招生类别 |
| 071000生物学 |
04细胞生物学 |
硕士学术学位 |
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