医学院
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| 导师代码： |
20720
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| 导师姓名： |
邬红
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| 性 别： |
女 |
| 特 称： |
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| 职 称： |
副研究员
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| 学 位： |
博士学位
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| 属 性： |
专职 |
| 电子邮件： |
wuhongzao@126.com
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| 学术经历：
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主要从事胸部肿瘤临床诊疗及临床试验研究工作，科学研究重点探索肿瘤免疫抑制性微环境调控、肿瘤耐药及肿瘤侵袭转移的机制；主持国家自然科学基金青年项目、国家博士后科学基金面上资助项目、四川省科技厅项目、中央高校项目等，参与科技部重大专项、国家自然科学基金面上项目；以第一作者在Journal of Clinical Investigation、Bioactive Materials、J EXP CLIN CANC RES、Cancer letters、Cancer research等SCI收录期刊论文10篇；申报国家发明专利4项。任四川省抗癌协会免疫治疗青委会委员、四川省抗癌协会肿瘤呼吸病青委会委员、肿瘤精准医学临床转化专委会秘书。
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| 个人简介：
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邬红，医学博士，博士后
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| 科研项目：
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| 研究成果：
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论文：
[1] Hong Wu, Yiqiang Liu, Qianshi Liu, Zhaoshen Li, Yejian Wan, Chenhui Cao, Binghuo Wu, MingXin Liu, Renchuan Liang, Lanlin Hu, Wenyi Zhang, Mei Lan, Quan Yao, Hang Zhou, Haitao Lan, Liang Chen, Yu Zhang, Xia Zhang, Xiuwu Bian, Chuan Xu; HMMR triggers immune evasion of hepatocellular carcinoma by inactivation of phagocyte killing; 2024, (SCI, Science Advances）（第一作者）
[2] Wu Hong, Len Xuefeng, Liu Qianshi, Mao Tianqin, Jiang Tao, Liu Yiqiang, Li Feifei, Cao Chenhui, Fan Jun, Yao Quan, Xia Zhang, Zhi-Xiong Jim Xiao, Lang Jinyi, Wang Guihua, Xu Chuan; Intratumoral Microbiota Composition Regulates Chemoimmunotherapy Response in Esophageal Squamous Cell Carcinoma; 2023, (SCI, Cancer Research）（第一作者）
[3] Hong Wu, Qianshi Liu, Jingpei Li, Xuefeng Leng, Yazhou He, Yiqiang Liu, Xia Zhang, Yang Liu, Wenhua Liang, Chuan Xu, Tumor-resident Microbiota-based Risk Prediction Model Predicts Response of Neo-adjuvant Therapy and Prognoses of Locally Advanced Esophageal Squamous Cancer Patients, 2024, (SCI, Advanced Science）（第一作者）
[4] Liu Q, Liu Y, Zhou Y, Liang L, Wan Y, Wang Y, Huang T, Zhong L, Li Z, Luo T, Zhao M, Li ZX, Li YC, Lan HT, Wu H, Xu C, Chen J; Intratumoral Lactobacillus johnsonii Enhances Sensitivity to PD-1 Blockade by Inducing CD8+ T-cell Expansion in Hepatocellular Carcinoma. Cancer Research; 2026, (SCI, Cancer Research）（共同通讯作者）
[5] Wu, Hong; Li, Hongyan; Liu, Yiqiang; Liang, Jingchen; Liu, Qianshi; Xu, Zhigang; Chen, Zh ongzhu; Zhang, Kun; Xu, Chuan ; Blockading a new NSCLC immunosuppressive target by pl uripotent autologous tumor vaccines magnifies sequential immunotherapy, 2021, 2022(13): 223-238 (SCI, Bioactive Materials) (第一作者）
[6] Xu, Chuan; Jin, Guoxiang; Wu, Hong; Cui Wei; Wang Yu-Hui; Manne Rajesh Kumar; Wang Guihua; Zhang Weina; Zhang Xian; Han Fei; Cai Zhen; Pan Bo-Syong; Hsu Che-Chia; Liu Yiqiang; Xie Dan; Bian Xiu-Wu; Lin Hui-Kuan ; SIRPγ-expressing cancer stem-like cells promote immune escape of lung cancer via Hippo signaling, 2022, 132(5) (SCI, Journal of Clinical Investigation)（共同第一作者）
[7] Hong Wu, Tao Wang , Yiqiang Liu, Xin Li, Senlin Xu, Changtao Wu, Hongbo Zou, Mianfu Cao, Jinyi Lang, Bin Wang, Baohua Liu, Xiaolin Luo and Chuan Xu. Mitophagy promotes sorafenib resistance through hypoxia-inducible ATAD3A dependent Axis; 2020,（JECCR）（第一作者）
[8] Tao Wang, Hong Wu, Sha Liu, Zengjie Lei, Zhongyi Qin, Liangzhi Wen, Yan Guo, Qin Liu, Lei Liu, Jun Wang, Li Lin, Chengyi Mao, Xiangfeng Zhu, Hualiang Xiao, Xiuwu Bian, Dongfeng Chen*, Chuan Xu*, Bin Wang*. SMYD3 controls a Wnt-responsive epigenetic switch for ASCL2 activation and cancer stem cell maintenance; 2019, (Article, SCI, Cancer letters)（共同第一作者）
[9] Liu, Yiqiang; Wu, Hong; Luo, Tao; Luo, Qiyu; Meng, Ziyu; Shi, Ying; Li, Feifei; Liu, Ming xin; Peng, Xinhao; Liu, Junjie; Xu, Chuan; Tang, Weizhong ; The SOX9-MMS22L Axis Promotes Oxalipl atin Resistance in Colorectal Cancer; 2021, (Article, Frontiers in Molecular Biosciences) （共同第一作者）
[10] Ziyu Meng, Binchao Wang, Yiqiang Liu, Yejian Wan, Qianshi Liu, Huasheng Xu, Renchuan Liang, Ying Shi, Peng Tu, Hong Wu, Chuan Xu；Mitochondria-targeting Polydopamine-coated Nanodrugs for Effective Photothermal- and Chemo- Synergistic therapies Against Lung Cancer；（Regenerative Biomateirals）（共同通讯作者）
专利：
[1]一种特异性表达人源性SIRPG的转基因小鼠的构建方法及其应用，国家发明专利，2012114053.5=
[2]一种预测肿瘤化疗联合免疫治疗疗效的标志物及其应用，国家发明专利，20211058224.4
[3]一种肿瘤抑制剂、其制备方法及应用，国家发明专利，202110315085.2
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| 专业研究方向：
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| 专业名称 |
研究领域/方向 |
招生类别 |
| 100200临床医学 |
07肿瘤学 |
硕士学术学位 |
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