光电科学与工程学院
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导师代码: |
20602
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导师姓名: |
陈琨
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性 别: |
男 |
特 称: |
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职 称: |
教授
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学 位: |
工学博士学位
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属 性: |
专职 |
电子邮件: |
chenk21@uestc.edu.cn
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学术经历:
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2009-2013年,南开大学学士。2013-2017年,清华大学博士。2017-2021年,加州大学伯克利分校博士后。现任电子科技大学教授、博士生导师。
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个人简介:
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陈琨,博士,教授,博士/硕士生导师。国家级海外高层次青年人才,电子科技大学百人计划入选者。主要从事光学成像和生命科学的前沿交叉研究工作,研究兴趣包括单分子光谱、超分辨显微成像、荧光光谱成像、非线性光谱成像、相干拉曼探测、超快激光器、活细胞动态成像等,以及新的成像手段在生命科学、化学材料的相关应用工作。迄今为止,在Nature Methods,Light: Science & Aplications, ACS Nano, J. Am. Chem. Soc., Developmental Cell, ACS Photonics, Optics Letters等期刊发表论文多篇。目前有专门的博士生、硕士生招生名额支持,欢迎光学、物理学、工程学、生物化学、细胞和分子生物学等学科的本科、硕士、博士生加入,我们希望的学生是勤奋好学、对知识渴求、自我驱动,创新技术,探索自然。
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科研项目:
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主持国家重点研发计划课题,国家自然基金委青年项目、面上项目,四川省自然科学基金等项目。
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研究成果:
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J. Yan, Y. He, K. Chen*. “Excitation spectral microscopy for highly multiplexed intracellular imaging via quasi-blind unmixing”. ACS Photonics. 11, 3454, 2024. [Virtual special issue “Rising Stars in Photonics”]
L. Xiang, R. Yan, K. Chen, W. Li, K. Xu*. “Single-molecule displacement mapping unveils sign-asymmetric protein charge effects on intraorganellar diffusion”. Nano Letters, 23, 1711, 2023
K. Chen, R. Yan, L. Xiang, K, Xu. “Excitation spectral microscopy for highly multiplexed fluorescence imaging and quantitative biosensing”. Light: Science & Applications. 10, 2021.
R. Yan, K. Chen, and K. Xu*. “SURF4-induced tubular ERGIC selectively expedites ER-to-Golgi transport.” Developmental Cell. 57, 1, 2022.
K. Chen, W. Li, and K. Xu*. “Super-multiplexing excitation spectral microscopy with multiple fluorescence bands.” Biomed. Opt. Express. 11, 6048, 2022.
L. Xiang||, K. Chen||, K. Xu*. “Single molecules are your quanta: A bottom-up approach toward multidimensional super-resolution microscopy”. ACS Nano. 15, 8, 2021. (||Equal contribution).
L, Xiang||, K. Chen||, R. Yan, W. Li, K, Xu. “Single-molecule displacement mapping unveils nanoscale heterogeneities in intracellular diffusivity”. Nature Methods, 7, 2020. (||Equal contribution).
R. Yan, K. Chen, and K. Xu. “Probing nanoscale diffusional heterogeneities in cellular membranes through multidimensional single-molecule and super-resolution microscopy.” J. Am. Chem. Soc. 44, 18866, 2020.
K. Chen, T. Wu, T. Chen, T. Zhou, H. Wei, Y. Li*. “Spectral focusing dual-comb coherent anti- Stokes Raman spectroscopic imaging”. Opt. Lett. 42, 3634, 2017.
K. Chen, T. Wu, Y. Li, H. Wei*. “Quantitative identification of chemical compounds by dual-soliton based coherent anti-Stokes Raman scattering spectroscopy”. Opt. Commun. 404, 177, 2017.
K. Chen, T. Wu, H. Wei, Y. Li*. “Dual-soliton Stokes based background-free CARS spectroscopy and microscopy”. Opt. Lett. 41, 2628, 2016.
K. Chen, T. Wu, T. Zhou, H. Wei, Y. Li*. “Cascaded dual-soliton pulse Stokes for broadband Coherent Anti-Stokes Raman Spectroscopy”. IEEE Photonics Journal. 8, 1, 2016.
K. Chen, T. Wu, H. Wei, T. Zhou, Y. Li*. “Quantitative chemical imaging with background-free multiplex coherent anti-Stokes Raman scattering by dual-soliton Stokes pulses”. Biomed. Opt. Express. 10, 3927, 2016.
K. Chen*, T. Wu, H. Wei*, X. Wu, Y. Li. “High spectral specificity of local chemical components characterization with multichannel shift-excitation Raman spectroscopy”. Sci. Rep. 5, 13952, 2015 (*Corresponding author).
K. Chen, H. Wei*, H. Zhang, T. Wu, Y. Li. “A Raman peak recognition method based automated fluorescence subtraction algorithm for retrieval of Raman spectra of highly fluorescent samples”. Ana. Methods, 7, 2770, 2015.
K. Chen*, H. Zhang, H, Wei, Y. Li. “Improved Savitzky–Golay-method-based fluorescence subtraction algorithm for rapid recovery of Raman spectra”. Applied optics 53, 5559, 2014 (*Corresponding author).
K. Chen, Y. Liang*, Y. Zhang. “Study on reflection of human skin with liquid paraffin as the penetration enhancer by spectroscopy”. Journal of biomedical optics 18, 105001, 2013.
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专业研究方向:
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专业名称 |
研究领域/方向 |
招生类别 |
080300光学工程 |
01光学与测量 |
博士学术学位 |
085400电子信息 |
01不区分研究方向,02不区分研究方向(非全) |
博士专业学位 |
080300光学工程 |
01光电技术与应用,02光电信息及传感技术 |
硕士学术学位 |
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