医学院
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| 导师代码： |
20186
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| 导师姓名： |
赵越
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| 性 别： |
女 |
| 特 称： |
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| 职 称： |
副研究员
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| 学 位： |
博士学位
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| 属 性： |
专职 |
| 电子邮件： |
zhaoyueyeah@126.com
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| 学术经历：
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美国康奈尔医学院附属Houston Methodist医院研究所 博士后
华中科技大学同济医学院附属同济医院 博士
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| 个人简介：
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赵越，副研究员/主治医师，肿瘤放射治疗方向，放疗中心/四川省放射肿瘤学重点实验室
四川省****青年人才项目
四川省卫生健康英才中青年骨干人才
四川省青联“科技之光”青年宣讲团讲师
四川省海外高层次留学人才
四川省免疫学会青委会副主任委员
四川省抗癌协会靶向专业委员会委员
四川省抗癌协会免疫专业委员会委员
四川省医促会鼻咽癌专业委员会委员
四川省医促会放射治疗与放射生物委员会委员
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| 科研项目：
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1. 国家自然科学基金青年项目，81903135，TRAF6/mTOR双向调控巨噬细胞极化在放疗联合PD-1抗体诱导远隔效应中的作用及机制研究，2020.01-2022.12，20.50万元，在研，主持
2. 国家自然科学基金青年项目，81300574，CORM-2阻断核内HMGB1释放的机制及其在肾缺血再灌注损伤中的保护作用研究，2014.01-2016.12，23万元，结题，参与
3. 国家自然科学基金面上项目，81172827，供体血管内皮细胞PDL1调控移植物血管病的机理和应用研究，2012.01-2015.12，55万元，结题，参与
4. 国家自然科学基金面上项目，81172825，HO-1高表达的供者源性tolDC过继输注诱导灵长类动物同种移植耐受，2012.01-2015.12，60万元，结题，参与
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| 研究成果：
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(1) Cao M, Wang Z, Lan W, Xiang B, Liao W, Zhou J, Liu X, Wang Y, Zhang S, Lu S, Lang J, Zhao Y. The roles of tissue resident macrophages in health and cancer. Exp Hematol Oncol. 2024 Jan 16;13(1):3. doi: 10.1186/s40164-023-00469-0 (中科院1区，IF=11.4)
(2) Level Ib CTV delineation in nasopharyngeal carcinoma based on lymph node distribution and topographic anatomy. Zhao Y, Liao X, Wang Y, Lan W, Ren J, Yang N, Li C, Lang J, Zhang S. Radiother Oncol. 2022 Jul;172:10-17. doi: 10.1016/j.radonc.2022.04.026. (中科院1区，IF=7.8)
(3) Zhao Yue (#); Chen Song; Lan Peixiang; Wu Chenglin; Dou Yaling; Xiao Xiang; Zhang Zhiqiang; Minze Laurie; He Xiaoshun; Chen Wenhao; Li Xian C. (*), Macrophage subpopulations and their impact on chronic allograft rejection versus graft acceptance in a mouse heart transplant model , American Journal of Transplantation, 2018.03, 18(3): 604~616 (中科院1区，IF=8.0)
(4) Zhao Yue(#) ; Jia Yu (#); Wang Lu; Chen Song; Huang Xia; Xu Bingyang; Zhao Guangyuan; Xiang Ying; Yang Jun; Chen Gang (*), Upregulation of Heme Oxygenase-1 Endues Immature Dendritic Cells With More Potent and Durable Immunoregulatory Properties and Promotes Engraftment in a Stringent Mouse Cardiac Allotransplant Model , Frontiers in Immunology, 2018.07.2, 9: 0~1515 (期刊论文)
(5) Zhao Yue (#); Lan Peixiang; Li Xian C (*) , Modulation of Innate Immune Cells to Create Transplant Tolerance, Springer International Publishing, 2017 (学术专著)
(6) Wu Chenglin (#); Zhao Yue; Xiao Xiang; Fan Yihui; Kloc Malgorzata; Liu Wentao; Ghobrial R M; Lan Peixiang; He Xiaoshun; Li Xian C, Graft-Infiltrating Macrophages Adopt an M2 Phenotype and Are Inhibited by Purinergic Receptor P2X7 Antagonist in Chronic Rejection , American Journal of Transplantation, 016.09, 16(9): 2563~2573 (期刊论文)
(7) Lan Peixiang (#); Fan Yihui; Zhao Yue; Lou Xiaohua; Monsour Howard P; Zhang Xiaolong; Choi Yongwon; Dou Yaling; Ishii Naoto; Ghobrial Rafik M; Xiao Xiang; Li Xian Chang, TNF superfamily receptor OX40 triggers invariant NKT cell pyroptosis and liver injury , Journal of Clinical Investigation, 2017.06.1, 127(6): 2222~2234 (期刊论文)
(8) Chen Wei (#); Zhao Yue; Li Xian C.; Kubiak Jacek Z.; Ghobrial Rafik M.; Kloc Malgorzata (*), Rho-specific Guanine nucleotide exchange factors (Rho-GEFs) inhibition affects macrophage phenotype and disrupts Golgi complex , International Journal of Biochemistry & Cell Biology, 2017.12, 93: 12~24 (期刊论文)
(9) Jia Yu(#); Zhao Yue; Wang Lu; Xiang Ying; Chen Song; Ming Chang Sheng; Wang Cong Yi; Chen Gang (*), Rat adipose-derived stem cells express low level of alpha-Gal and are dependent on CD59 for protection from human xenoantibody and complement-mediated lysis , American Journal of Translational Research, 2016, 8(5): 2059~2069 (期刊论文)
(10) Ruan Yongle (#); Wang Lu (#); Zhao Yue; Yao Ying; Chen Song; Li Junhua; Guo Hui; Ming Changsheng; Chen Shi; Gong Feili; Chen Gang(*) , Carbon monoxide potently prevents ischemia-induced high-mobility group box 1 translocation and release and protects against lethal renal ischemia-reperfusion injury , Kidney International, 2014.09, 86(3): 525~537 (期刊论文)
(9) Zhao Yue; Chen Wenhao; Lan Peixiang; Xiao Xiang; Liu Wentao; Kloc Malgorzata; Liu Yianzhu; Ghobiral R; Gaber O; Li Xian C, Conditional Knock out of mTOR in myeloid cells inhibits chronic allograft rejection a novel role for macrophages in transplant vasculopathy, American Transplant congress, Boston,
MA, 2016.6.10-2016.6.13
(10) Zhao Yue; Chen Wenhao; Liu Wentao; Kloc Malgosia; Ghobrial Rafik; Lan Peixiang; Li Xian C, Macrophage-specific deletion of mTOR inhibits chronic allograft rejection and induces long-term heart allograft survival, The Transplant Society Congress, Hong Kong, 2016.8.18-2016.8.23
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| 专业研究方向：
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| 专业名称 |
研究领域/方向 |
招生类别 |
| 100200临床医学 |
07肿瘤学 |
硕士学术学位 |
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