医学院


 
导师代码: 20182
导师姓名: 杨牧
性    别:
特    称:
职    称: 教授
学    位: 博士学位
属    性: 专职
电子邮件: mu.yang@uestc.edu.cn

学术经历:  

个人简介:   杨牧,博士,教授,博士研究生导师。2012年至2019年供职于加拿大McGill大学附属Montréal Neurological Hospital and Institute。2019年4月至今供职于四川省肿瘤医院,任肿瘤实验研究部主任。主要研究方向:1、记忆通胀介导重大疾病演进的免疫学机制;2、宿主免疫异质性的生物学原理与干预策略。发表论文70余篇,总影响因子约330,单篇最高他引500余次。

科研项目:   主持加拿大CIHR、Catherine Bushnell Foundation和四川省国际科技创新合作重大项目等国家和省部级基金8项。

研究成果:   1. Shi Z, Wang X, Wang J, Chen H, Du Q, Lang Y, Kong L, Luo W, Qiu Y, Zhang Y, Li C, Wen D, Yao J, Cheng X, Cai L, Lin X, Wang R, Mou Z, Li S, Liu D, Zhou H, Zhou H, Yang M., Granzyme B + CD8 + T cells with terminal differentiated effector signature determine multiple sclerosis progression. J Neuroinflammation. 2023 Jun 2;20(1):138. IF=9.6/JCR1 2. He Q, Zhou Y, Zhou J, Zhao D, Li L, Li X, Huang Y, Wang Q, Zou H, Zhang K, Li Y, Wang Z, Deng Y, Meng F, Ying B, Yang M, Wang D., Clinical relevance of plasma EBV DNA as a biomarker for nasopharyngeal carcinoma in non-endemic areas: A multicenter study in southwestern China. Clin Chim Acta. 2023 Feb 15;541:117244. IF=6.3/JCR2 3. Shi Z, Du Q, Wang X, Wang J, Chen H, Lang Y, Kong L, Luo W, Yang M, Zhou H., Granzyme B in circulating CD8+ T cells as a biomarker of immunotherapy effectiveness and disability in neuromyelitis optica spectrum disorders. Front Immunol. 2022 Nov 9;13:1027158. IF=8.8/JCR1 4. Wen D, Wang X, Chen R, Li H, Zheng J, Fu W, Zhang T, Yang M, You C, Ma L., Single-Cell RNA Sequencing Reveals the Pathogenic Relevance of Intracranial Atherosclerosis in Blood Blister-Like Aneurysms. Front Immunol. 2022 Jul 8;13:927125. IF=8.8/JCR1 5. Wen D, Chen R, Li H, Zheng J, Fu W, Shi Z, You C, Yang M, Ma L., Reduced M2 macrophages and adventitia collagen dampen the structural integrity of blood blister-like aneurysms and induce preoperative rerupture. Cell Prolif. 2022 Feb;55(2):e13175. IF=8.8/JCR1 6. Liu X, Yu Z, Wu Y, Shi S, Yao J, Feng X, Wen D, Shi Z, Zhao Z, Li Y, Zhou H, You C, Lin Y, Yang M., The immune regulatory effects of tetrahedral framework nucleic acid on human T cells via the mitogen-activated protein kinase pathway. Cell Prolif. 2021 Aug;54(8):e13084. IF=8.8/JCR1 7. Oladiran O, Shi XQ, Yang M, Fournier S, Zhang J., Inhibition of TLR4 signaling protects mice from sensory and motor dysfunction in an animal model of autoimmune peripheral neuropathy. J Neuroinflammation. 2021 Mar 22;18(1):77. IF=9.6/JCR1 8. Shi Z, Qiu Y, Zhao Z, Wen D, Chen H, Du Q, Zhang Y, Wang J, Yan C, Yang M, Zhou H., CD8+ T cell subpopulations and pro-inflammatory cytokines in neuromyelitis optica spectrum disorder. Ann Clin Transl Neurol. 2021 Jan;8(1):43-53. IF=5.4/JCR1 9. Wen D, Kieran NW, Yang M., Letter by Wen et al Regarding Article, "Pathophysiology of Intracranial Aneurysms: COX-2 Expression, Iron Deposition in Aneurysm Wall, and Correlation With Magnetic Resonance Imaging". Stroke. 2020 Dec;51(12):e367-e368. IF=10.2/JCR1 10. Wen D, Xiao Y, Yang M., Letter by Wen et al Regarding Article, "Increased Wall Enhancement During Follow-Up as a Predictor of Subsequent Aneurysmal Growth". Stroke. 2020 Oct;51(10):e293-e294. IF=10.2/JCR1 11. Shi Z, Du Q, Chen H, Zhang Y, Qiu Y, Zhao Z, Wang J, Yan C, Zhang Q, Yang M, Zhou H., Effects of immunotherapies and prognostic predictors in neuromyelitis optica spectrum disorder: a prospective cohort study. J Neurol. 2020 Apr;267(4):913-924. IF=6.7/JCR1 12. Zhang F, Ren Y, Fu W, Wang Y, Qian J, Tao C, You C, Yang M., Association between neutrophil to lymphocyte ratio and blood glucose level at admission in patients with spontaneous intracerebral hemorrhage. Sci Rep. 2019 Oct 30;9(1):15623. IF=5/JCR2 13. Wen D, Ma L, Yang M., Letter by Wen et al Regarding Article, "Validation of Wall Enhancement as a New Imaging Biomarker of Unruptured Cerebral Aneurysm". Stroke. 2019 Oct;50(10):e305. IF=10.2/JCR1 14. Yang M, Shi XQ, Peyret C, Oladiran O, Wu S, Chambon J, Fournier S, Zhang J., Effector/memory CD8+ T cells synergize with co-stimulation competent macrophages to trigger autoimmune peripheral neuropathy. Brain Behav Immun. 2018 Jul;71:142-157. IF=19.2/JCR1 15. Wang GYF, Shi XQ, Wu W, Gueorguieva M, Yang M, Zhang J., Sustained and repeated mouth opening leads to development of painful temporomandibular disorders involving macrophage/microglia activation in mice. Pain. 2018 Jul;159(7):1277-1288. IF=7.9/JCR1 16. Echeverry S, Shi XQ, Yang M, Huang H, Wu Y, Lorenzo LE, Perez-Sanchez J, Bonin RP, De Koninck Y, Zhang J., Spinal microglia are required for long-term maintenance of neuropathic pain. Pain. 2017 Sep;158(9):1792-1801. IF=7.9/JCR1 17. Yao Y, Echeverry S, Shi XQ, Yang M, Yang QZ, Wang GY, Chambon J, Wu YC, Fu KY, De Koninck Y, Zhang J., Dynamics of spinal microglia repopulation following an acute depletion. Sci Rep. 2016 Mar 10;6:22839. IF=5/JCR2 18. Yang M, Peyret C, Shi XQ, Siron N, Jang JH, Wu S, Fournier S, Zhang J., Evidence from Human and Animal Studies: Pathological Roles of CD8(+) T Cells in Autoimmune Peripheral Neuropathies. Front Immunol. 2015 Oct 15;6:532. IF=8.8/JCR1 19. Sorge RE, Mapplebeck JC, Rosen S, Beggs S, Taves S, Alexander JK, Martin LJ, Austin JS, Sotocinal SG, Chen D, Yang M, Shi XQ, Huang H, Pillon NJ, Bilan PJ, Tu Y, Klip A, Ji RR, Zhang J, Salter MW, Mogil JS., Different immune cells mediate mechanical pain hypersensitivity in male and female mice. Nat Neurosci. 2015 Aug;18(8):1081-3. IF=28.8/JCR1 20. Yang M, Rainone A, Shi XQ, Fournier S, Zhang J., A new animal model of spontaneous autoimmune peripheral polyneuropathy: implications for Guillain-Barré syndrome. Acta Neuropathol Commun. 2014 Jan 8;2:5. IF=7.6/JCR1

专业研究方向:
专业名称 研究领域/方向 招生类别
107200生物医学工程 01医学基础研究 博士学术学位
071000生物学 04细胞生物学 硕士学术学位


学院列表
01  信息与通信工程学院
02  电子科学与工程学院
03  材料与能源学院
04  机械与电气工程学院
05  光电科学与工程学院
06  自动化工程学院
07  资源与环境学院
08  计算机科学与工程学院(网络空间安全学院)
09  信息与软件工程学院(示范性软件学院)
10  航空航天学院
11  数学科学学院
12  物理学院
13  医学院
14  生命科学与技术学院
15  经济与管理学院
16  公共管理学院
17  外国语学院
18  马克思主义学院
21  基础与前沿研究院
22  通信抗干扰全国重点实验室
23  电子科学技术研究院
28  电子科技大学(深圳)高等研究院
31  集成电路科学与工程学院(示范性微电子学院)
90  智能计算研究院