医学院
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导师代码: |
12029
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导师姓名: |
谈颂
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性 别: |
女 |
特 称: |
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职 称: |
教授
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学 位: |
医学博士学位
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属 性: |
专职 |
电子邮件: |
153620904@qq.com
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学术经历:
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中华医学会神经病学专第八届委员会委员, 中华医学会神经病学专第八届委员会神经肌肉病学组委员,中国医院协会罕见病专委会第一届委员,四川省康复医学会神经病学专委会周围神经肌肉病学组组长,四川省医学会神经病学分会神经免疫学组副组长。既往在脑血管病领域,具有良好的科研素质,并取得相关成绩。目前主要科研方向为神经肌病和神经免疫,牵头建立肌肉病理诊治平台,获院创新技术二等奖。曾赴荷兰乌特勒支大学医学中心做访问学者一年,师从著名神经病学家Jan van Gijn教授。曾获2012年省级医学科技创新成果二等奖,排名第3。发表高水平论文20余篇,国家自然基金课题1项、省级项目1项,厅局级1项、纵向管理的横向课题1项。电子科技大学医学院本科《神经病学》课程负责人。2018四川省首届“新时代健康卫士”称号;第十一批四川省学术和技术带头人后备人选;第十三批四川省卫生健康委学术技术带头人后备人选。
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个人简介:
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共产党员,博士(四川大学华西医院2005年博士毕业),博士后(2010年出站),神经内科主任医师/副教授,硕导。电子科技大学医学院临床医学系副主任,四川省人民医院神经内科副主任、教研室副主任,神内规培基地教学主任,四川省人民医院罕见病中心副主任。从事神经病学工作20余年,有良好的临床、教学及科研经历和经验。目前从事的研究方向为神经免疫和周围神经肌肉病的基础和临床研究,第十一批四川省学术和技术带头人后备人选;第十三批四川省卫生健康委学术技术带头人后备人选。
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科研项目:
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1. 国家自然科学基金-青年基金项目,81501026,TRPM在神经细胞缺血损伤中作用及DREAM对TRPM7调控机制研究,2016/1-2018/12,17.5万元,主持;
2. 四川省人力资源和社会保障厅-省学术和技术带头人培养支持经费,[2017]919号,TRPM7在神经元缺氧损伤中的作用及上游调控机制研究,在研中,主持;
3. 教育部科学技术研究项目-重点项目,NGII20170722,基于深度学习的干式穿戴ECG设备在隐源性卒中患者中房颤筛查方面的应用,2018.3.9-2019.12.31,主持;
4. 国家自然科学基金面上基金项目,:人诱导多能干细胞衍生的少突胶质细胞祖细胞治疗缺血性脑损伤的研究,81771238, 2018.1-2021.12;第一主研
5.国家自然科学基金-青年基金项目:UBQLN2-蛋白酶通路在亨廷顿包涵体聚集及毒性中的作用及机制研究,81801270,2019.1-2021.12,第二主研
6.四川省科技厅重点研发项目:脑卒中院前急救血压管理的多中心随机对照临床研究及平台建设,2021YFS0376,2021.7.1-2024.7.31,主持
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研究成果:
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1.Yuan R, Tan S, Wang D, Wu S, Cao X, Zhang S, Wu B, Liu M. Predictive value of plasma matrix metalloproteinase-9 concentrations for spontaneous haemorrhagic transformation in patients with acute ischaemic stroke: A cohort study in Chinese patients. J Clin Neurosci. 2018 Dec;58:108-112. PubMed PMID: 30287248.(IF:1.64) 共同第一
2.Tan S, Wang RH, Niu HX, Shi CH, Mao CY, Zhang R, Song B, Sun SL, Liu XJ, Hou HM, Liu YT, Gao Y, Fang H, Kong XD, Xu YM*, Nerve Growth Factor for the Treatment of Spinocerebellar Ataxia Type 3: An Open-label Study, Chin Med J (Engl), 2015, 128(3): 291-294
3.Tan S, Wang D, Liu M, Zhang S, Wu B, Liu B, Frequency and predictors of spontaneous hemorrhagic transformation in ischemic stroke and its association with prognosis, J Neurol, 2014, 261(5): 905-912(IF: 3.46)PMID: 24590407
4.Tan S, Niu HX, Zhao L, Gao Y, Lu JM, Shi CH, Avinash C, Wang RH, Xu YM. Reliability and validity of the Chinese version of the Scale for Assessment and Rating of Ataxia. Chin Med J (Engl). 2013;126(11):2045-8. PubMed PMID: 23769555. (IF: 0.952)
5.钟庆玲 曾莉 谈颂. 免疫检查点抑制剂相关神经肌病.华西医学 2020,(6):734-737 (通讯作者)
6.Ji Y, Tan S, Xu Y, Chandra A, Shi C, Song B, Qin J, Gao Y. Vitamin B supplementation, homocysteine levels, and the risk of cerebrovascular disease: a meta-analysis. Neurology. 2013 Oct 8;81(15):1298-307. PubMed PMID: 24049135.(IF: 8.312)
7.Wang HL, Tan S, Song B, Miao W, Gao Y, Zhao L, Lu JM, Xu YM. Correlation of H-type hypertension and prognosis of ischemic stroke. Zhonghua Yi Xue Za Zhi. 2012 May 8;92(17):1183-6. Chinese. PubMed PMID: 22883006. (Medline)
8.Jiang S, Luo C, Gong J, Peng R, Ma S, Tan S, Ye G, Dong L, Yao D.Aberrant Thalamocortical Connectivity in Juvenile Myoclonic Epilepsy.Int J Neural Syst. 2018 Feb;28(1):1750034(IF:6.333)
9.Jinnan Gong, Xuebin Chang, Si si Jiang, Benjamin Klugah-Brown Song Tan, Dezhong Yao, Cheng Luo. Microstructural alterations of white matter in juvenile myoclonic epilepsy. Epilepsy research.2017,135:1-8. (IF:2.237)
10.Shi CH, Schisler JC, Rubel CE, Tan S, Song B, McDonough H, Xu L, Portbury AL, Mao CY, True C, Wang RH, Wang QZ, Sun SL, Seminara SB, Patterson C, Xu YM. Ataxia and hypogonadism caused by the loss of ubiquitin ligase activity of the U box protein CHIP. Hum Mol Genet. 2013 Oct 16. PMID:24113144.(IF: 7.692)
11.Chen H, Zhang Q, Tan S, Fu H, Farris BK, Yang Z. Update on the application of optic nerve sheath fenestration. Restor Neurol Neurosci. 2017;35(3):275-286. PubMed PMID: 28339414. (IF: 2.526)
12.Zhao L, Wang R, Song B, Tan S, Gao Y, Fang H, Lu J, Xu Y. Association between atherogenic dyslipidemia and recurrent stroke risk in patients with different subtypes of ischemic stroke. Int J Stroke. 2015 Jul;10(5):752-8. doi:10.1111/ijs.12471. Epub 2015 Apr 28. PubMed PMID: 25924059.
13.Song B, Fang H, Zhao L, Gao Y, Tan S, Lu J, Sun S, Chandra A, Wang R, Xu Y. Validation of the ABCD3-I score to predict stroke risk after transient ischemic attack. Stroke. 2013 May;44(5):1244-8. PubMed PMID: 23532014.(IF:5.729)
14.Xie Y, Li YH, Chen K, Zhu CY, Bai JY, Xiao F, Tan S, Zeng L. Key biomarkers and latent pathways of dysferlinopathy: Bioinformatics analysis and in vivo validation. Front Neurol. 2022 Sep 20;13:998251. PMID: 36203997
15.Yang L, Qin Y, Chen K, Xu C, Peng M, Tan S, Liu T, Yao D. The role of basal ganglia network in neural plasticity in neuromyelitis optica spectrum disorder with myelitis. Mult Scler Relat Disord. 2022 Sep 9;68:104170. PMID: 36113277.(共同通讯)
16.Zhou Y, Chen J, Li Z, Tan S, Yan C, Luo S, Zhou L, Song J, Huan X, Wang Y, Zhao C, Zeng W, Xi J. Clinical Features of Myasthenia Gravis With Antibodies to MuSK Based on Age at Onset: A Multicenter Retrospective Study in China. Front Neurol. 2022 Apr 8;13:879261.PMID: 35463138
17.Jiao K, Dong J, Luo S, Yu L, Ke Q, Wang Z, Luan X, Zhang X, Guo J, Chen Y, Li X, Tan S, Qian F, Jiang J, Yu X, Yue D, Liu C, Luo L, Li J, Qu Y, Chen L, Tu J, Sun C, Yan C, Song J, Xi J, Lin J, Lu J, Zhao C, Zhu W, Fang Q. High-risk screening of late-onset Pompe disease: A different early portrait in China. Front Neurol. 2022 Sep 27;13:965207. doi: 10.3389/fneur.2022.965207. PMID: 36237614.
18.Liu Y, Zeng L, Yuan Y, Wang Y, Chen K, Chen Y, Bai J, Xiao F, Xu Y, Yang J, Tan S. Case report: Two siblings with neuronal intranuclear inclusion disease exhibiting distinct clinicoradiological findings. Front Neurol. 2022 Oct 25;13:1013213. doi: 10.3389/fneur.2022.1013213. PMID: 36388211; (IF:4.003)(通讯作者)
19.Wang DZ, Li BH, Ma Q, Yu Z, Chen K, He Y, Tan S. Novel compound heterozygous mutations of LAMA2-limb-girdle muscular dystrophy: A case report and literature review. Front Neurol. 2023 Feb 13;14:1078151. doi: 10.3389/fneur.2023.1078151. PMID: 36860576;(通讯作者)
20.Zhong H, Ruan Z, Yan C, Lv Z, Zheng X, Goh LY, Xi J, Song J, Luo L, Chu L, Tan S, Zhang C, Bu B, Da Y, Duan R, Yang H, Luo S, Chang T, Zhao C; Pan-Yangtze River Delta Alliance for Neuromuscular Disorders (PYDAN). Short-term outcome prediction for myasthenia gravis: an explainable machine learning model. Ther Adv Neurol Disord. 2023 Feb 24;16:17562864231154976. doi: 10.1177/17562864231154976. PMID: 36860354
21.Li Z, Cheng L, Xu Y, Sun Q, Zhang J, Bai L, Feng T, Tan S, Wang H, Deng B, Li Q, Gui Y, Chen H. Optic Nerve Sheath Fenestration for Progressive Visual Loss in Cerebral Venous Sinus Thrombosis: A Long-Term Retrospective Observational Study. Neurol Ther. 2023 Jan 7. doi: 10.1007/s40120-022-00434-9. Epub ahead of print. PMID: 36609961.
22.Yang M, Lin Y, Cheng H, Zheng D, Tan S, Zhu L, Li Z, Wang X, Yang J. Excessive Supraventricular Ectopic Activity and the Risk of Atrial Fibrillation and Stroke: A Systematic Review and Meta-Analysis. J Cardiovasc Dev Dis. 2022 Dec 15;9(12):461. doi: 10.3390/jcdd9120461. PMID: 36547459
23.Yang L, Li W, Xie Y, Ma S, Zhou X, Huang X, Tan S. Impact of dysautonomic symptom burden on the quality of life in Neuromyelitis optica spectrum disorder patients. BMC Neurol. 2023 Mar 20;23(1):112. doi: 10.1186/s12883-023-03162-1. PMID: 36941592
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专业研究方向:
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专业名称 |
研究领域/方向 |
招生类别 |
105104神经病学 |
01不区分招生研究方向 |
硕士专业学位 |
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