医学院
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| 导师代码： |
21178
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| 导师姓名： |
熊萱
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| 性 别： |
女 |
| 特 称： |
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| 职 称： |
副研究员
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| 学 位： |
理学硕士学位
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| 属 性： |
专职 |
| 电子邮件： |
xiongxuan@med.uestc.edu.cn
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| 学术经历：
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本科毕业于中南大学湘雅医学院，硕士毕业于四川大学华西药学院。
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| 个人简介：
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副主任药师，现任四川省抗癌协会肿瘤临床药学专委会委员，四川省生物信息学学会医疗健康信息传播分会委员，成都药学会药事管理专委会委员兼秘书，四川省医学会临床药学专委会青委会委员兼秘书。
发表论文30余篇，其中以第一作者/通讯发表SCI论文10余篇，参编著作3部，副主编1部，获专利3项。长期从事个体化药物治疗。研究方向：循证药学、生物信息学。
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| 科研项目：
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作为课题负责人主持省厅级课题5项，参研国家级、省厅级课题多项；共计经费超30万。
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| 研究成果：
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发表的部分论文
1. Li Siwen,Xie Jiaqi,Li Keman,et al.Mulberrin alleviates triclocarban induced hepatic apoptosis and inflammation by regulating the ROS/NF-κB pathway in grass carp. Comparative Biochemistry And Physiology Toxicology & Pharmacology : CBP,2023,273: 109734. (通讯作者CA)
2. Li Siwen, Xie Jiaqi, Li Xinlian,et al.Genistein protects benzotriazole ultraviolet stabilizer UV-234-induced hepatotoxicity by modulating ROS/Nrf2 and NF-κB signaling in yellow catfish (Pelteobagrus fulvidraco).Comparative Biochemistry And Physiology Toxicology & Pharmacology : CBP,2023,271:109675 (通讯作者CA)
3. Xiong Xuan, Zhang Xiaoqin, Zhang Yuan, et al. Sarco/endoplasmic reticulum Ca2+ ATPase (SERCA)-mediated ER stress crosstalk with autophagy is involved in tris(2-chloroethyl) phosphate stress-induced cardiac fibrosis. Journal of inorganic biochemisty, 2022, 236（第一作者FA1/3）
4. Li Siwen, Wang Yanling,Yu Dongke,et al.Triclocarban evoked neutrophil extracellular trap formation in common carp (Cyprinus carpio L.) by modulating SIRT3-mediated ROS crosstalk with ERK1/2/p38 signaling. FISH & SHELLFISH IMMUNOLOGY, 2022,129:85-95 (通讯作者CA)
5. Zhao Liyun, Xiong Xuan, Liu Li, et al. Recent research and development of DYRK1A inhibitors. CHINESE CHEMICAL LETTERS,2022,33(4):1841-1849 （第一作者FA2/3）
6. Zhang Yuan, Wang Jingjing, Xiong Xuan, et al. Suicidality in patients with primary diagnosis of panic disorder: A single-rate meta-analysis and systematic review. Journal of affective disorders, 2022,300:27-33（第一作者FA3/3）
7. Lingai Pan, Dongke Yu, Yuan Zhang, Changyu Zhu, Qinan Yin, Yu Hu, Xiaoqin Zhang, Ruiming Yue, Xuan Xiong. Polystyrene microplastics-triggered mitophagy and oxidative burst via activation of PERK pathway, Science of The Total Environment, 2021,781 (通讯作者CA)
8. Xiong X, Xiao H, Zhang Y, et al. Diagnosis Test Meta-Analysis for Apolipoprotein E in Alzheimer's Disease. Dis Markers. 2020,2020:6486031 (第一作者FA1/3)
9. Xiong Xuan, Yu Dongke, Gao Qiaoyue, et al. Association between CYP2B6 c.516G >T variant and acute leukaemia A protocol for systematic review and meta-analysis. MEDICINE, 2021,100:(32):e26740 (第一作者FA1/3)
10. Zhang Y, He X, Xiong X, et al. The association between maternal methylenetetrahydrofolate reductase C677T and A1298C polymorphism and birth defects and adverse pregnancy outcomes. Prenat Diagn. 2019;39(1):3-9 (第一作者FA3/3)
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| 专业研究方向：
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| 专业名称 |
研究方向 |
招生类别 |
| 105500药学 |
01临床药学 |
硕士专业学位 |
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