导师个人信息 - 电子科大研招网

医学院

导师代码：	21164
导师姓名：	肖培宏
性别：	男
特称：
职称：	副研究员
学位：	理学博士学位
属性：	专职
电子邮件：	peihongxiao@uestc.edu.cn

学术经历：

2022.08 - 至今，电子科技大学附属四川省人民医院，副研究员； 2021.04 - 2022.05，香港科技大学，联合培养博士后； 2019.10 - 2022.05，深圳大学AIE研究中心，博士后； 2013.09 - 2018.06，四川大学，理学博士；2009.09 - 2013.06，四川大学，本科。

个人简介：

肖培宏，四川省人民医院副研究员，课题组长。四川省自然科学基金杰出青年基金获得者，四川省医学会精准医学专业委员会青年委员，Exploration、Nano TransMed期刊青年编委，四川省卫生健康英才计划中青年骨干人才，四川省人民医院“双百工程”-优秀青年业务干部。主要从事疾病诊疗一体化探针开发及检验新技术与新方法研究，近5年共发表SCI论文18篇，所发表论文累计他引627次。主持国家自然科学基金青年基金1项，四川省自然科学基金杰出青年基金1项，中国博士后科学基金面上资助1项，授权中国发明专利3项。

科研项目：

1. 国家自然科学基金青年科学基金：基于聚集诱导发光的深红/近红外荧光探针的合成及其在细菌成像和光动力杀菌中的应用研究，项目批准号：22007067，主持，已结题。 2. 四川省自然科学基金杰出青年基金：肿瘤微环境激活型近红外二区诊疗一体化探针的构建及应用研究，项目批准号：24NSFJQ0067, 主持，在研； 3. 中国博士后科学基金第67批面上资助：高尔基体靶向的聚集诱导发光诊疗一体化探针的设计、合成及应用研究，项目批准号：2020M672768，主持，已结题。

研究成果：

代表性论文： (1) Chenqi Guo, Mengying Wu, Zhaofei Guo, Rongping Zhang, Zijun Wang, Xiong Peng, Jianxia Dong, Xun Sun, Zhirong Zhang, Peihong Xiao*, Tao Gong*, Hypoxia-Responsive Golgi-Targeted Prodrug Assembled with Anthracycline for Improved Antitumor and Antimetastasis Efficacy, ACS Nano, 2023, 17, 24972-24987. (IF = 17.100) (2) Peihong Xiao#, Wei Xie#, Jianyu Zhang, Qian Wu, Zipeng Shen, Chenqi Guo, Yi Wu, Fubing Wang*, Ben Zhong Tang*, Dong Wang*. De Novo Design of Reversibly pH-Switchable NIR-II Aggregation-Induced Emission Luminogens for Efficient Phototheranostics of Patient-Derived Tumor Xenografts, J. Am. Chem. Soc., 2023, 145, 334-344. (IF = 16.806) (3) Yu Lan, Haixia Zhang, Ruichen Xie, Kecheng Li, Feiran Xie, Peihong Xiao*, Li Jiang*. An endoplasmic reticulum-targeted NIR fluorescent nanoprobe for early diagnosis of glaucoma in vivo, Sensors and Actuators B: Chemical, 2024, 406, 135441. (IF = 8.400) (4) Peihong Xiao; Zipeng Shen; Deliang Wang; Yinzhen Pan; Ying Li*; Junyi Gong; Lei Wang; Dong Wang*; Ben Zhong Tang*. Precise Molecular Engineering of Type I Photosensitizers with Near-Infrared Aggregation-Induced Emission for Image-Guided Photodynamic Killing of Multidrug Resistant Bacteria, Adv. Sci., 2022, 9, 2104079. (IF = 16.823) (5) Peihong Xiao#; Ke Ma#; Miaomiao Kang; Luyi Huang; Qian Wu; Nan Song;Jinyin Ge; Dan Li; Jianxia Dong; Lei Wang; Dong Wang*; Ben Zhong Tang*. An aggregation-induced emission platform for efficient Golgi apparatus and endoplasmic reticulum specific imaging, Chem. Sci., 2021, 12, 13949-13957. (IF = 9.825) (6) Peihong Xiao; Lu Gao; Zhenlei Song*. Recent Progress in the Transition-Metal-Catalyzed Activation of Si-Si Bonds to Form C-Si Bonds, Chem. Eur. J., 2019, 25, 2407-2422. (IF = 5.160) (7) Peihong Xiao; Yanjun Cao; Yingying Gui; Lu Gao; Zhenlei Song*. Me3Si-SiMe2[o-CON (iPr)2-C6H4]: An Unsymmetrical Disilane Reagent for Regio- and Stereoselective Bis-Silylation of Alkynes, Angew. Chem. Int. Ed., 2018, 57, 4769-4773. (inside cover，IF = 15.336) (8) Peihong Xiao, Zhixing Tang, Kai Wang, Hua Chen, Qianyou Guo, Yang Chu, Lu Gao* and Zhenlei Song*, Chemoselective Reduction of Sterically Demanding N, N-di (iso-propyl) Amides to Aldehydes. J. Org. Chem. 2018, 83, 1687？1700. (Featured article, Cover paper, IF = 4.849) (9) Zhijun Zhang, Wenhan Xu, Peihong Xiao, Miaomiao Kang, Dingyuan Yan, Haifei Wen, Nan Song, Dong Wang*, and Ben Zhong Tang*, Molecular Engineering of High-Performance Aggregation-Induced Emission Photosensitizers to Boost Cancer Theranostics Mediated by Acid-Triggered Nucleus-Targeted Nanovectors, ACS Nano 2021, 15, 10689-10699. (IF = 15.881) (10) Dan Li, Youmei Li, Qian Wu, Peihong Xiao, Lei Wang, Dong Wang*, Ben Zhong Tang*, Add the Finishing Touch: Molecular Engineering of Conjugated Small Molecule for High-Performance AIE Luminogen in Multimodal Phototheranostics, Small 2021, 17, 2102044. (IF = 13.281) (11) Ying Li, Fei Liu, Jiangjiang Zhang, Xiaoye Liu, Peihong Xiao, Haotian Bai, Shang Chen, Dong Wang, Simon H. P. Sung, Ryan T. K. Kwok, Jianzhong Shen, Kui Zhu*, Ben Zhong Tang*, Efficient Killing of Multidrug-Resistant Internalized Bacteria by AIEgens In Vivo, Adv. Sci. 2021, 8, 2001750. (IF = 16.823) (12) Xiujuan Shi，Simon H. P. Sung，Joe H. C. Chau，Ying Li，Zhiyang Liu，Ryan T. K. Kwok， Junkai Liu，Peihong Xiao，Jiangjiang Zhang，Bin Liu，Jacky W. Y. Lam，Ben Zhong Tang* Killing G(+) or G(-) Bacteria? The Important Role of Molecular Charge in AIE-Active Photosensitizers. Small Methods 2020, 4, 2000046. (IF = 12.130) (13) Zengjin Liu, Xinglong Lin, Na Yang, Zhishan Su, Changwei Hu, Peihong Xiao, Yanyang He, and Zhenlei Song*，Unique Steric Effect of Geminal Bis(silane) To Control the High Exo-selectivity in Intermolecular Diels–Alder Reaction. J. Am. Chem. Soc., 2016, 138, 1877–1883. (IF = 14.357) (14) Changzhen Sun，Yuebao Zhang, Peihong Xiao, Hongze Li, Xianwei Sun, and Zhenlei Song* Intramolecular [1,4]-S- to O-Silyl Migration: A Useful Strategy for Synthesizing Z-Silyl Enol Ethers with Diverse Thioether Linkages.Org. Lett., 2014, 16, 984–987. (IF = 6.492)

专业研究方向：